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| Yu Hanyang Professor Address: Room 1412, Mong Manwai Building, Gulou Campus, Nanjing University Tel: 025-83593177 Email: hanyangyu@nju.edu.cn Lab homepage: http://yulab.nju.edu.cn |
| Research field
Courses Biochemistry Profile Professor Yu received his bachelor’s from the School of Life and Sciences, Peking University. In 2013, he received his doctorate in biochemistry from Arizona State University and went to Dieter Söll Lab at Yale University for post-doctoral research. In 2015, he was selected into the 11th group of the Overseas Young Scholars Project of China and joined the Department of Biomedical Engineering, College of Engineering and Applied Science, Nanjing University. His research is to isolate non-natural aptamers through in vitro screening and explore their application to the diagnosis and treatment of epigenetics-related diseases. He has published his research results on top-notch chemistry journals such as Nature Chemistry and Journal of the American Chemical Society. Research results Publications: (Note: † refers to equal contributor.) [1] Yu, Hanyang, Zhang, Su, Dunn, Matthew R., & Chaput, John C. (2013). An efficient and faithful in vitro replication system for threose nucleic acid. Journal of the American Chemical Society, 135(9), 3583-3591. [2] Yu, Hanyang,† Zhang, Su,† & Chaput, John C. (2012). Darwinian evolution of an alternative genetic system provides support for TNA as an RNA progenitor. Nature Chemistry, 4(3), 183. [3] Yu, Hanyang, Jiang, Bing, & Chaput, John C. (2011). Aptamers can discriminate alkaline proteins with high specificity. ChemBioChem, 12(17), 2659-2666. [4] Chaput, John C., Yu, Hanyang, & Zhang, Su. (2012). The emerging world of synthetic genetics. Chemistry & Biology, 19(11), 1360-1371. [5] Zhang, Su, Yu, Hanyang, & Chaput, John C. (2013). Synthesis of Threose Nucleic Acid (TNA) Triphosphates and Oligonucleotides by Polymerase-Mediated Primer Extension. Current Protocols in Nucleic Acid Chemistry, 52(1), 4-54. [6] Liu, Rui, Jiang, Bing, Yu, Hanyang, & Chaput, John C. (2011). Generating DNA synbodies from previously discovered peptides. ChemBioChem, 12(12), 1813-1817. Patents: [1] Chaput, John, Yu, Hanyang, Zhang, Su, & Dunn, Matthew R. (2013). Methods and compositions for replication of threose nucleic acids. U.S. Patent US2014/010062. Others Graduate students advisement Professor Yu recruits one or two doctoral students and two or three master’s students each year. Professor Yu and his team welcome those willing to join the team as postdoctoral researchers or visiting scholars. Those who are interested please email hanyangyu@nju.edu.cn.
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